Forschung

Lehrstuhl für Pädiatrie am MCO

Die Kinderklinik Bayreuth engagiert sich in der klinischen und translationalen Forschung mit Schwerpunkt auf praxisrelevanten Fragestellungen der Pädiatrie und Neonatologie.

Forschungsschwerpunkte umfassen unter anderem Neonatologie, pädiatrische Infektiologie und Versorgungsforschung.

In Kooperation mit der Biophysik Erlangen (Dr.Navid Bonakdar) beteiligt sich unser Forschungsteam (Prof. Dr. Patrick Morhart) an einem innovativen Forschungsprojekt mit interdisziplinärer Ausrichtung. Ziel des Projekts ist es die invasive und nichtinvasive Beatmung sowie die tracheale Absaugung vor allem bei Früh- und Neugeborenen zu verbessern.

https://www.med.fau.de/2025/10/20/intelligentes-absaugsystem-schuetzt-fruehgeborene/ Ansprechpartner/-innen in der Kinderklinik für Doktorarbeiten sind Dr. phil. Dr.med. Heidi Weberruss, Dr. med Petros Strempas und Prof. Dr. Patrick Morhart.


Eine Auswahl relevanter Publikationen finden sich nachfolgend:

  • Bär, A., et al., Evaluating the Use of Neonatal Colonization Screening for Empiric Antibiotic Therapy of Sepsis and Pneumonia. Antibiotics (Basel), 2023. 12(2).
  • Baumgartner, L., et al., Longitudinal association of peak oxygen uptake with vascular and cardiac structure and function in German pediatric athletes. Am J Physiol Heart Circ Physiol, 2025. 329(4): p. H959–h968.
  • Esse, J., et al., Metagenomic analysis of microbial cell-free DNA from plasma of patients with suspected infections: performance and therapeutic impact in clinical routine. Clin Microbiol Infect, 2025. 31(6): p. 1018–1025.
  • Grieshaber-Bouyer Mandelbaum, H., et al., Sensing ultrasound localization microscopy for ultrastructural and functional imaging of neonatal kidneys. Ultraschall Med, 2025.
  • Morhart, P., et al., Age-related Differences in Immune Reactions to SARS-CoV-2 Spike and Nucleocapsid Antigens. In Vivo, 2023. 37(1): p. 70–78.
  • Morhart, P., et al., Maternal SARS-CoV-2 infection during pregnancy: possible impact on the infant. Eur J Pediatr, 2022. 181(1): p. 413–418.
  • Härtel, C., et al., Association of Administration of Surfactant Using Less Invasive Methods With Outcomes in Extremely Preterm Infants Less Than 27 Weeks of Gestation. JAMA Netw Open, 2022. 5(8): p. e2225810.
  • Hébert, S., et al., „Multisystem Inflammatory Syndrome in Children“ (MIS-C) after COVID-19 Infection in the Metropolitan Area of Nuremberg-Erlangen, Germany-Expectations and Results of a Two-Year Period. Children (Basel), 2023. 10(8).
  • Hofbauer, A., et al., [SARS-CoV-2 Infection in Pregnancy and Incidence of Congenital Malformations – is there a Correlation? Analysis of 8032 Pregnancies from the CRONOS Registry]. Z Geburtshilfe Neonatol, 2024. 228(1): p. 65–73.
  • Körber, I., et al., Safety and immunogenicity of Fc-EDA, a recombinant ectodysplasin A1 replacement protein, in human subjects. Br J Clin Pharmacol, 2020. 86(10): p. 2063–2069.
  • Meyer, S., et al., Early postnatal high-dose fat-soluble enteral vitamin A supplementation for moderate or severe bronchopulmonary dysplasia or death in extremely low birthweight infants (NeoVitaA): a multicentre, randomised, parallel-group, double-blind, placebo-controlled, investigator-initiated phase 3 trial. Lancet Respir Med, 2024. 12(7): p. 544–555.
  • Morhart, P., et al., Influence of Timing of Antenatal Corticosteroid Administration on Morbidity of Preterm Neonates. In Vivo, 2022. 36(4): p. 1777–1784.
  • Morhart, P., et al., Application of Next-Generation Sequencing to Enterobacter Hormaechei Subspecies Analysis during a Neonatal Intensive Care Unit Outbreak. Children (Basel), 2023. 10(10).
  • Mulzer, L.M., et al., Premature birth associated with a favorable course in gestational alloimmune liver disease (GALD): A case report. Front Pediatr, 2023. 11: p. 1104530.
  • Poryo, M., et al., Two-year outcomes after early postnatal high-dose fat-soluble enteral vitamin A supplementation in extremely low birth weight infants: follow-up of the NeoVitaA randomized controlled trial. EClinicalMedicine, 2025. 89: p. 103495.
  • Schleier, M., et al., Diagnostic Utility of Interleukin-6 in Early-Onset Sepsis among Term Newborns: Impact of Maternal Risk Factors and CRP Evaluation. Children (Basel), 2023. 11(1).
  • Schuh, W., et al., A surrogate cell-based SARS-CoV-2 spike blocking assay. Eur J Immunol, 2021. 51(11): p. 2665–2676.
  • Schüssler, S.C., et al., Seizures in preterm infants with germinal-matrix-intraventricular hemorrhage (GM-IVH): a retrospective monocentric study on predictors and neurodevelopmental outcome. Eur J Paediatr Neurol, 2025. 56: p. 51–57.
  • Semmler, L., et al., Mediative role of body mass index in cardiorespiratory fitness-associated vascular remodeling in youth. Pediatr Res, 2025. 97(6): p. 1997–2004.
  • Strempas, P., et al., Analysis of Pathogens in Respiratory Tract Infections and Their Effect on Disease Severity: Retrospective Data from a Tertiary Care German Children’s Hospital. Children (Basel), 2025. 12(4).
  • van der Donk, A., et al., Development of the EPO-Score – a multivariable tool to predict adverse outcome in infants with perinatal asphyxia undergoing therapeutic hypothermia – a retrospective study. Front Pediatr, 2025. 13: p. 1627300.
  • Weigelt, A., et al., Impact of premature birth on cardiopulmonary function in later life. Eur J Pediatr, 2023. 182(7): p. 3265–3274.
  • Wolff, J., et al., [Development of a standardized handover for critically ill premature and newborn infants for interhospital transport in Bavaria]. Z Geburtshilfe Neonatol, 2025. 229(5): p. 331–337.
  • Zipf, S., et al., First postnatal lactate blood levels on day 1 and outcome of preterm infants with gestational age <29 weeks. Front Pediatr, 2024. 12: p. 1443066.